3-Bromo-1-propanol → HCID 68514762, compound

Participants

Reaction Steps

A mixture of 10.0 g (0.072 mol) of 1,4,6-trimethylpyrimidin-2(1H)-one and 20.6 g (0.144 mol) of 3-bromopropanol was heated under reflux in acetonitrile for 16 hours under an inert gas atmosphere. After cooling, a pale pink-colored solid precipitated out, which was filtered off with suction (starting material). The filtrate was admixed with chloroform, then the same amount of diethyl ether was added. The product separated out in the form of an oil.

Provenance & Evidence