HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 3-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-pyrazol-4-yl]-5,6,7,8,9,10-hexahydro-cycloocta[c]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 1,2-Cyclooctanedione | HCID 543698 | — |
| Reactant | {2-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-pyrazol-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester | HCID 86609912 | — |
| Product | 3-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-pyrazol-4-yl]-5,6,7,8,9,10-hexahydro-cycloocta[c]pyridazine | HCID 16063591 | — |
Reaction Steps
off-white solid. MS (EI): 390.1 (M+). Prepared from cyclooctane-1,2-dione, {2-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-pyrazol-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester, hydrazine monohydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07678795B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-2832930200994ddbba3ceea0f88f3461 |
| Source note | uspto-grants-2010_03 |