Hydrazine hydrate (1:1) → (1SR,8RS)-5-(1-Methyl-1H-pyrrol-2-yl)-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

HRID 2243937Notes

Reaction equation

HRID 2243937 reaction equation
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[C:3](=O)[C:2]2=O.COP([CH2:16][C:17]([C:19]1[N:20]([CH3:24])[CH:21]=[CH:22][CH:23]=1)=O)(=O)OC.O.[NH2:26][NH2:27]>>[CH3:24][N:20]1[CH:21]=[CH:22][CH:23]=[C:19]1[C:17]1[CH:16]=[C:3]2[C:2]([CH:1]3[CH2:7][CH:4]2[CH2:5][CH2:6]3)=[N:27][N:26]=1

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 138696Bicyclo(2.2.1)heptane-2,3-dioneHCID 86609923[2-(1-Methyl-1H-pyrrol-2-yl)-2-oxo-ethyl]-phosphonic acid dimethyl ester

Product 1

HCID 67363905(1SR,8RS)-5-(1-Methyl-1H-pyrrol-2-yl)-3,4-diaza-tricyclo[6.2.1.02,7]undeca-2,4,6-triene

Procedure

off-white solid. MS (EI): 225.29 (M+). Prepared from bicyclo[2.2.1]heptane-2,3-dione, [2-(1-Methyl-1H-pyrrol-2-yl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-74d2ad541b184444ac50f981ae301dfb
Source dataset
uspto-grants-2010_03
Patent number
US07678795B2

Reaction notes

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