Hydrazine hydrate (1:1) → HCID 67363485, compound

HRID 2243942Notes

Reaction equation

HRID 2243942 reaction equation
[CH3:1][C@@:2]12[C:8]([CH3:10])([CH3:9])[C@@H:5]([CH2:6][CH2:7]1)[C:4](=O)[C:3]2=O.COP([CH2:19][C:20]([C:22]1[CH:27]=[C:26]([F:28])[CH:25]=[CH:24][C:23]=1[O:29][CH3:30])=O)(=O)OC.O.[NH2:32][NH2:33]>>[F:28][C:26]1[CH:25]=[CH:24][C:23]([O:29][CH3:30])=[C:22]([C:20]2[CH:19]=[C:4]3[C:3]([C@:2]4([CH3:1])[C:8]([CH3:10])([CH3:9])[C@H:5]3[CH2:6][CH2:7]4)=[N:33][N:32]=2)[CH:27]=1

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 1549179(+)-CamphorquinoneHCID 86609926HCID 86609926, compound

Product 1

HCID 67363485HCID 67363485, compound

Procedure

light yellow solid. MS (ESI): 312.9 (MH+). Prepared from (1S,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptane-2,3-dione, [2-(5-Fluoro-2-methoxy-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-3be7156486984ff1a36521f8931d4988
Source dataset
uspto-grants-2010_03
Patent number
US07678795B2

Reaction notes

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