Hydrazine hydrate (1:1) → HCID 67363498, compound

HRID 2243957Notes

Reaction equation

HRID 2243957 reaction equation
[CH3:1][C@@:2]12[C:8]([CH3:10])([CH3:9])[C@@H:5]([CH2:6][CH2:7]1)[C:4](=O)[C:3]2=O.COP([CH2:19][C:20]([C:22]1[CH:23]=[N:24][N:25]([C:30]([CH3:33])([CH3:32])[CH3:31])[C:26]=1[CH:27]1[CH2:29][CH2:28]1)=O)(=O)OC.O.[NH2:35][NH2:36]>>[C:30]([N:25]1[C:26]([CH:27]2[CH2:29][CH2:28]2)=[C:22]([C:20]2[CH:19]=[C:4]3[C:3]([C@:2]4([CH3:1])[C:8]([CH3:10])([CH3:9])[C@H:5]3[CH2:6][CH2:7]4)=[N:36][N:35]=2)[CH:23]=[N:24]1)([CH3:33])([CH3:32])[CH3:31]

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 1549179(+)-CamphorquinoneHCID 86609930HCID 86609930, compound

Product 1

HCID 67363498HCID 67363498, compound

Procedure

yellow solid. MS (ESI): 351.2 (MH+). Prepared from (1S,4R)-1,7,7-trimethyl-bicyclo[2.2.1]heptane-2,3-dione, [2-(1-tert-Butyl-5-cyclopropyl-1H-pyrazol-4-yl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-d0d1ef19812b4fa8a3313ef1c8585c9e
Source dataset
uspto-grants-2010_03
Patent number
US07678795B2

Reaction notes

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