HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminophenol → {4-[(3,5-Difluoropyridin-4-yl)oxy]phenyl}amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminophenol | HCID 403 | — |
| Reactant | 3,4,5-Trifluoropyridine | HCID 16181465 | — |
| Reactant | 4-(3-Aminophenoxy)pyridine-2-carboxamide | HCID 23137229 | — |
| Product | {4-[(3,5-Difluoropyridin-4-yl)oxy]phenyl}amine | HCID 57833527 | — |
Reaction Steps
{4-[(3,5-Difluoropyridin-4-yl) oxy]phenyl} amine (2E) was prepared by a method analogous to that described for 4-(3-aminophenoxy) pyridine-2-carboxamide (2C), starting from 4-aminophenol and 3, 4, 5-trifluoropyridine, MS ES: 223 (M+H)+, calcd 223, RT=0.50 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07678804B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-02ed669ff5cc432b9a2283d080a925dc |
| Source note | uspto-grants-2010_03 |