HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Chlorophenoxyacetyl chloride → 10-[(4-Chlorophenoxy)acetyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Chlorophenoxyacetyl chloride | HCID 77771 | — |
| Reactant | 10,11-Dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine | HCID 15547048 | — |
| Reactant | 10-[(4-Chloro-2-methylphenoxy)acetyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine | HCID 68681019 | — |
| Product | 10-[(4-Chlorophenoxy)acetyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine | HCID 68680429 | — |
Reaction Steps
This compound was prepared from 10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine and 4-chlorophenoxyacetyl chloride in the same manner as the preparation of 10-[(4-chloro-2-methylphenoxy)acetyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine of Example 139, Step B, m.p. 120-122° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07678787B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-e409af0b14b64b59a6187a3c016ba381 |
| Source note | uspto-grants-2010_03 |