HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-Chloro-2-(2-hydroxy-benzyl)-phenoxy]-acetic acid methyl ester → 2-[2-(5-Chloro-2-methoxycarbonylmethoxy-benzyl)-phenoxy]-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-Chloro-2-(2-hydroxy-benzyl)-phenoxy]-acetic acid methyl ester | HCID 68451833 | — |
| Reactant | 2-[2-(2-Benzyloxycarbonylmethoxy-5-chloro-benzyl)-4-chloro-phenoxy]-propionic acid | HCID 68452550 | — |
| Product | 2-[2-(5-Chloro-2-methoxycarbonylmethoxy-benzyl)-phenoxy]-propionic acid | HCID 68452789 | — |
Reaction Steps
The titled compound is prepared analogously to 2-[2-(2-benzyloxycarbonylmethoxy-5-chloro-benzyl)-4-chloro-phenoxy]-propionic acid by replacing [4-chloro-2-(5-chloro-2-hydroxy-benzyl)-phenoxy]-acetic acid benzyl ester with [4-chloro-2-(2-hydroxy-benzyl)-phenoxy]-acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07678826B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-584e1bfaa2ba487fb58f715989400f8e |
| Source note | uspto-grants-2010_03 |