HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Methylthiobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Methylthiobenzoic acid | HCID 178425911 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 4-Methylthiobenzoyl chloride | HCID 15555005 | 80% |
Reaction Steps
A mixture of 56 mmol (8.85 g) p-methylthiobenzoic acid, 40 ml benzene and 112 mmol (7.4 ml) thionyl chloride is boiled under reflux for 24 hours. The benzene and excess thionyl chloride are removed under vacuum to give p-methylthiobenzoyl chloride mp 48-52 in 80% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04232038 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-66e188364a464f80ba2ce746e11591ff |
| Source note | uspto-grants-1980_11 |