HRID2244664

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11194854

4-(4-aminophenyl)morpholin-3-one

C10H12N2O2

结构：COC(=O)[C@@H]1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](O)C1

HCID58826431

未命名化合物

PRODUCTS

生成物

结构：O=C(N[C@H]1C[C@@H](C(=O)Nc2ccc(N3CCOCC3=O)cc2)C[C@@H]1O)c1ccc(Cl)s1

HCID16066321

未命名化合物

PROCEDURE

实验过程

In analogy to example 1C, (1R,3S,4S)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-4-hydroxy-cyclopentanecarboxylic acid methyl ester (example 1B) was reacted with 4-(4-amino-phenyl)-morpholin-3-one (CAS 438056-69-0) to give 5-chloro-thiophene-2-carboxylic acid {(1S,2S,4R)-2-hydroxy-4-[4-(3-oxo-morpholin-4-yl)-phenylcarbamoyl]-cyclopentyl}-amide. Yellow solid. MS: 464.4 ([M+H]+)