huagongshe.com
HRID2244668

反应详情

EQUATION

反应方程式

HRID 2244668 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@@H]1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](O)C1
HCID58826431

未命名化合物

结构：Cc1cc(-n2ccccc2=O)ccc1N
HCID66882353

1-(4-Amino-3-methylphenyl)pyridin-2(1H)-one

C12H12N2O

PRODUCTS

生成物

1
结构：Cc1cc(-n2ccccc2=O)ccc1NC(=O)[C@@H]1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](O)C1
HCID16066159

未命名化合物

PROCEDURE

实验过程

In analogy to example 1C, (1R,3S,4S)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-4-hydroxy-cyclopentanecarboxylic acid methyl ester (example 1B) was reacted with 1-(4-amino-3-methyl-phenyl)-1H-pyridin-2-one to give 5-chloro-thiophene-2-carboxylic acid {(1S,2S,4R)-2-hydroxy-4-[2-methyl-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-cyclopentyl}-amide. Off-white solid. MS: 472.4 ([M+H]+).