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HRID2244669

反应详情

EQUATION

反应方程式

HRID 2244669 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc(-n2ccccc2=O)cc1
HCID11535695

1-(4-AMINOPHENYL)-1H-PYRIDIN-2-ONE

C11H10N2O

结构：COC(=O)[C@@H]1C[C@H](NC(=O)c2ccc(Cl)s2)[C@@H](O)C1
HCID58826431

未命名化合物

PRODUCTS

生成物

1
结构：O=C(N[C@H]1C[C@@H](C(=O)Nc2ccc(-n3ccccc3=O)cc2)C[C@@H]1O)c1ccc(Cl)s1
HCID16066158

未命名化合物

PROCEDURE

实验过程

In analogy to example 1C, (1R,3S,4S)-3-[(5-chloro-thiophene-2-carbonyl)-amino]-4-hydroxy-cyclopentanecarboxylic acid methyl ester (example 1B) was reacted with 1-(4-amino-phenyl)-1H-pyridin-2-one (CAS 13143-47-0) to give 5-chloro-thiophene-2-carboxylic acid {(1S,2S,4R)-2-hydroxy-4-[4-(2-oxo-2H-pyridin-1-yl)-phenyl-carbamoyl]-cyclopentyl}-amide. Orange solid. MS: 458.3 ([M+H]+).