Sodium borohydride → HCID 54463040, compound

HRID 224472Notes

Reaction equation

HRID 224472 reaction equation
[CH3:1][C:2]1[CH:8]=[C:7]([OH:9])[C:6]([C:10](=[O:26])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[C:5]([CH2:27][CH2:28][CH3:29])[C:3]=1[OH:4].[BH4-].[Na+]>CO.O>[CH3:1][C:2]1[CH:8]=[C:7]([OH:9])[C:6]([CH:10]([OH:26])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[C:5]([CH2:27][CH2:28][CH3:29])[C:3]=1[OH:4]

Participants

5

Reactant 2

HCID 4311764Sodium borohydrideHCID 23333245HCID 23333245, compound

Product 1

HCID 54463040HCID 54463040, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolvent2×HCID 962WaterSolvent

Procedure

6.5 g of the keto-compound of step 4 were dissolved in 90 ml of methanol and hydrogenated with a solution of 0.75 g of sodium borohydride in 8 ml of water as described for compound 17, step 5. The crude carbinol formed was recrystallized from methanol.

Workup

  1. customwas recrystallized from methanol

Sources & evidence

ORD record
ord-a233c85a4cb54d76b87318407b04cbf8
Source dataset
uspto-grants-1980_11
Patent number
US04232107

Reaction notes

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