HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → HCID 68544128, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 1-(2-bromoethyl)-1H-pyrazole | HCID 642215 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68544128 | HCID 68544128 | 50% |
Reaction Steps
A solution of 1-(2-bromoethyl)pyrazole [6d] (12 mmol) in tetrahydrofuran was added dropwise to a solution of ethylenediamine (0.24 mol) in water. The mixture was refluxed for 4 hours. The THF was removed under vacuum and the water phase was washed with dichloromethane. After drying under vacuum resulted a yellow oil which was formulated as pz(CH2)2NH(CH2)2NH2 (1). Yield: 50%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07682601B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-7c8eda593d6c4b59a76a846090f7cdc6 |
| Source note | uspto-grants-2010_03 |