Hydrochloric Acid → HCID 68682751, compound

Participants

Reaction Steps

A solution of 20.0 grams (0.075 mole) of 4-pyridyl 4-(trifluoromethoxy)phenyl ketone in 350 mL of ethanol was stirred as hydrogen chloride gas was bubbled through during a five minute period. Upon completion of addition, the reaction mixture was stirred for one hour, and then it was filtered to collect a solid. The solid was washed with three portions of diethyl ether, and dried in a vacuum oven, yielding about 22.0 grams of the subject compound. The NMR spectrum was consistent with the proposed structure.

Provenance & Evidence