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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2245516Generated: November 3, 2026

Lithium Hydroxide → N-[4-({5-[(Phenylsulfonyl)amino]-1H-indol-1-yl}methyl)benzoyl]-L-phenylalanine

https://huagongshe.com/reaction/2245516

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantBenzenesulfonyl chlorideHCID 7369—
Reactantethyl N-{4-[(5-amino-1H-indol-1-yl)methyl]benzoyl}phenylalaninateHCID 68548160—
ProductN-[4-({5-[(Phenylsulfonyl)amino]-1H-indol-1-yl}methyl)benzoyl]-L-phenylalanineHCID 16113884—

Reaction Steps

Treatment of ethyl N-{4-[(5-amino-1H-indol-1-yl)methyl]benzoyl}phenylalaninate with benzenesulfonyl chloride followed by LiOH hydrolysis as described in the procedure of Example 1 gave the title compound: MS (ESI) m/z 554; MS (ESI) m/z 552.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07683091B2
Source datasetuspto-grants-2010_03
ORD IDord-7ec04104ea414eee8125fd23f7c21450
Source noteuspto-grants-2010_03