p-(Trifluoromethoxy)benzenesulphonyl chloride → N-(4-{[5-({[4-(Trifluoromethoxy)phenyl]sulfonyl}amino)-1H-indol-1-yl]methyl}benzoyl)-L-phenylalanine

Participants

Role	Name	HCID	Charge
Reactant	p-(Trifluoromethoxy)benzenesulphonyl chloride	HCID 523102	—
Reactant	ethyl N-{4-[(5-amino-1H-indol-1-yl)methyl]benzoyl}phenylalaninate	HCID 68548160	—
Product	N-(4-{[5-({[4-(Trifluoromethoxy)phenyl]sulfonyl}amino)-1H-indol-1-yl]methyl}benzoyl)-L-phenylalanine	HCID 16113885	—

Reaction Steps

The title compound was prepared from ethyl N-{4-[(5-amino-1H-indol-1-yl)methyl]benzoyl}phenylalaninate and 4-trifluoromethoxyphenyl sulfonyl chloride following the procedure of Example 10: MS (ESI) m/z 638; MS (ESI) m/z 636.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07683091B2
Source dataset	uspto-grants-2010_03
ORD ID	ord-574681e9cd4a4a3d9ffe5916382a1728
Source note	uspto-grants-2010_03