HRID2245521

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID74192

(1,1'-Biphenyl)-4-sulphonyl chloride

C12H9ClO2S

HCID458475

3-Aminopropionic acid ethyl ester hydrochloride

C5H12ClNO2

结构：O=C(O)c1ccc(Cn2ccc3cc([N+](=O)[O-])ccc32)cc1

HCID59216708

未命名化合物

PRODUCTS

生成物

结构：O=C(O)CCNC(=O)c1ccc(Cn2ccc3cc(NS(=O)(=O)c4ccc(-c5ccccc5)cc4)ccc32)cc1

HCID16113882

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 4-[(5-nitro-1H-indol-1-yl)methyl]benzoic acid, β-alanine ethyl ester hydrochloride, and biphenyl 4-sulfonyl chloride following the procedure of Example 10: MS (ESI) m/z 554; MS (ESI) m/z 552.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0c6d79a5eab34c938fed3fe09d88dee1
来源数据集: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07683091B2
来源说明: uspto-grants-2010_03

反应 SMILES

[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[N:9]([CH2:13][C:14]1[CH:22]=[CH:21][C:17]([C:18](O)=[O:19])=[CH:16][CH:15]=1)[CH:8]=[CH:7]2)([O-])=O.Cl.C([O:26][C:27](=[O:31])[CH2:28][CH2:29][NH2:30])C.[C:32]1([C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=2)[CH:37]=[CH:36][C:35]([S:38](Cl)(=[O:40])=[O:39])=[CH:34][CH:33]=1>>[C:32]1([C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=2)[CH:37]=[CH:36][C:35]([S:38]([NH:1][C:4]2[CH:5]=[C:6]3[C:10](=[CH:11][CH:12]=2)[N:9]([CH2:13][C:14]2[CH:15]=[CH:16][C:17]([C:18]([NH:30][CH2:29][CH2:28][C:27]([OH:26])=[O:31])=[O:19])=[CH:21][CH:22]=2)[CH:8]=[CH:7]3)(=[O:40])=[O:39])=[CH:34][CH:33]=1