HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-4-sulphonyl chloride → N-[4-({5-[(1,1'-Biphenyl-4-ylsulfonyl)amino]-1H-indol-1-yl}methyl)benzoyl]-beta-alanine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
| Reactant | beta-Alanine, ethyl ester, hydrochloride | HCID 458475 | — |
| Reactant | 4-[(5-Nitro-1H-indol-1-yl)methyl]benzoic acid | HCID 59216708 | — |
| Product | N-[4-({5-[(1,1'-Biphenyl-4-ylsulfonyl)amino]-1H-indol-1-yl}methyl)benzoyl]-beta-alanine | HCID 16113882 | — |
Reaction Steps
The title compound was prepared from 4-[(5-nitro-1H-indol-1-yl)methyl]benzoic acid, β-alanine ethyl ester hydrochloride, and biphenyl 4-sulfonyl chloride following the procedure of Example 10: MS (ESI) m/z 554; MS (ESI) m/z 552.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07683091B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-0c6d79a5eab34c938fed3fe09d88dee1 |
| Source note | uspto-grants-2010_03 |