Potassium Carbonate → HCID 59216455, compound

HRID 2245721Notes

Reaction equation

HRID 2245721 reaction equation
F[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[O:11])[CH2:6][CH2:5]2.Cl.[NH:13]1[CH2:16][CH2:15][CH2:14]1.C([O-])([O-])=O.[K+].[K+]>CS(C)=O>[N:13]1([C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[C:7](=[O:11])[CH2:6][CH2:5]3)[CH2:16][CH2:15][CH2:14]1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 1365375-Fluoro-1-indanoneHCID 12308726Azetidine hydrochloride

Product 1

HCID 59216455HCID 59216455, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

5-fluoro-1-indanone (7.44 g, 49.5 mmol), Azetidine HCl (5.1 g, 54.4 mmol) and K2CO3 (13.6 g, 99 mmol) were taken up in 60 ml of DMSO. The reaction mixture was heated at 100 C for 6 hours.

Workup

  1. temperatureThe reaction mixture was heated at 100 C for 6 hours

Sources & evidence

ORD record
ord-2c9e5f322bf64f3b9670b6f9437b58aa
Source dataset
uspto-grants-2010_03
Patent number
US07683064B2

Reaction notes

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