HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,6-Diamino-3-methyl-1-phenyluracil → 3,7-dihydro-1-methyl-3-phenyl-8-propyl-1H-purine-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,6-Diamino-3-methyl-1-phenyluracil | HCID 11075275 | — |
| Solvent | Butyric anhydride | HCID 7798 | — |
| Product | 3,7-dihydro-1-methyl-3-phenyl-8-propyl-1H-purine-2,6-dione | HCID 23331678 | — |
Reaction Steps
A solution of 3 g of 5,6-diamino-3-methyl-1-phenyl-2,4-(1H, 3H)-pyrimidinedione XVIII in 25 ml of butyric anhydride was refluxed for 16 hours. After cooling, grey crystals were filtered off and recrystallized from 100 ml of ethanol. Yield 1.1 g NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04233303 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-7bb604bf4dae465d9037e14ba509730b |
| Source note | uspto-grants-1980_11 |