Hydrochloric Acid → HCID 59217491, compound

HRID 2246028Notes

Reaction equation

HRID 2246028 reaction equation
[ClH:1].[CH3:2][C:3]1([CH2:9][OH:10])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1.[CH2:11]=O>CCCCCC>[Cl:1][CH2:11][O:10][CH2:9][C:3]1([CH3:2])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 1501840(1-Methylcyclohexyl)methanol

Product 1

HCID 59217491HCID 59217491, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Under ice cooling and stirring, hydrogen chloride was blown into a mixture of 128 g of (1-methylcyclohexyl)methanol, 400 g of hexane, and 36 g of paraformaldehyde, until the is reactant alcohol disappeared on gas chromatography analysis. The excess hydrogen chloride was purged by feeding nitrogen into the reactor, after which the water layer was removed by separatory operation. The solution was dried over magnesium sulfate and the solids filtered off, yielding a hexane solution of chloromethyl[(1-methylcyclohexyl)methyl] ether.

Workup

  1. customThe excess hydrogen chloride was purged
  2. customafter which the water layer was removed by separatory operation
  3. dry with materialThe solution was dried over magnesium sulfate
  4. filtrationthe solids filtered off

Sources & evidence

ORD record
ord-8a95cc2396ca423c92f952919432958a
Source dataset
uspto-grants-2010_03
Patent number
US07687222B2

Reaction notes

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