Benzenemethanamine, N-(phenylmethylene)- → HCID 12370119, compound

HRID 2246051Notes

Reaction equation

HRID 2246051 reaction equation
[CH:1](=[N:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:16]([CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])#[C-:17]>C(O)C>[CH2:1]([N:8]1[CH:9]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:18]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:16]=[CH:17]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 95831Benzenemethanamine, N-(phenylmethylene)-HCID 533707Ethyl isocyanoacetate

Product 1

HCID 12370119HCID 12370119, compoundYield 99.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

25.7 g (0.1305 mol) of benzylidenebenzylamine were dissolved in ethanol, and 15.2 g (0.1305 mol) of ethyl isocyanoacetate were added dropwise. The solution was heated under reflux for 16 h. Removal of the solvents and drying gave 40.2 g of the title compound as a colorless oil.

Workup

  1. temperatureThe solution was heated
  2. temperatureunder reflux for 16 h
  3. customRemoval of the solvents
  4. customdrying

Sources & evidence

ORD record
ord-56e7ec9e50a14f75a58b149d8bdc9efb
Source dataset
uspto-grants-2010_03
Patent number
US07687435B2

Reaction notes

Loading…