HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenemethanamine, N-(phenylmethylene)- → Ethyl 1-benzyl-5-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenemethanamine, N-(phenylmethylene)- | HCID 95831 | — |
| Reactant | Ethyl isocyanoacetate | HCID 533707 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 1-benzyl-5-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate | HCID 12370119 | 99.9% |
Reaction Steps
25.7 g (0.1305 mol) of benzylidenebenzylamine were dissolved in ethanol, and 15.2 g (0.1305 mol) of ethyl isocyanoacetate were added dropwise. The solution was heated under reflux for 16 h. Removal of the solvents and drying gave 40.2 g of the title compound as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687435B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-56e7ec9e50a14f75a58b149d8bdc9efb |
| Source note | uspto-grants-2010_03 |