HRID2246134

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7841

Allyl bromide

C3H5Br

HCID11166

3-Iodo-1-propene

C3H5I

$结构：C[C@@H](O)[C@H]1C(=O)N2C(C(=O)[O-])=C(S/C=C\c3scnc3CO)[C@H](C)[C@H]12.[Na+]$

HCID23676797

未命名化合物

PRODUCTS

生成物

$结构：C=CCOC(=O)C1=C(S/C=C\c2scnc2CO)[C@H](C)[C@@H]2[C@@H]([C@@H](C)O)C(=O)N12$

HCID69471839

未命名化合物

收率 94.2%

PROCEDURE

实验过程

In the same manner as in Example 81, 984 mg of the title compound was prepared from 1.00 g of sodium (1R,5S,6S)-6-((1R)-1-hydroxyethyl)-2-[[(Z)-2-(4-hydroxymethylthiazol-5-yl)ethen-1-yl]thio]-1-methyl-1-carbapen-2-em-3-carboxylate prepared in Example 41, 538 mg of allyl bromide, and 415 mg of allyl iodide.