HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2246237Generated: November 1, 2026
Hydroxylamine → 2-Fluoro-N'-hydroxy-4-(methanesulfonyl)benzene-1-carboximidamide
https://huagongshe.com/reaction/2246237
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | 2-Fluoro-4-(methylsulfonyl)benzonitrile | HCID 22346425 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Fluoro-N'-hydroxy-4-(methanesulfonyl)benzene-1-carboximidamide | HCID 71413608 | — |
Reaction Steps
To a stirred solution of the product from Step E (0.29 g, 0.144 mmol) in ethanol (15 mL) was added hydroxylamine (50% in water, 3.0 mL). The reaction was heated at 90° C. for 3 h. The reaction was then concentrated to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07687492B2 |
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| Source dataset | uspto-grants-2010_03 |
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| ORD ID | ord-c72f38cdac23496b9ee55ba9e6cbc827 |
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| Source note | uspto-grants-2010_03 |
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