Methyl (2S)-2-[(1S)-1-[(tert-butoxycarbonyl)amino]-2-oxo-2-pyrrolidin-1-ylethyl]pent-4-enoate → Methyl (2S)-2-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-oxo-2-pyrrolidin-1-ylethyl}pentanoate

Participants

Reaction Steps

To a stirred solution of the product from Step B (1.54 g) in ethyl acetate (30 mL) was added 5% palladium on carbon (298 mg). The reaction mixture was stirred under hydrogen (1 atm) at room temperature for 2 h, then filtered through a pad of Celite and concentrated to give the desired product.

Provenance & Evidence