2-Aminothiazole → HCID 11501028, compound

HRID 2246249Notes

Reaction equation

HRID 2246249 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9](I)[CH:10]=2)[N:5]=[CH:4][N:3]=1.[NH2:13][C:14]1[S:15][CH:16]=[CH:17][N:18]=1.[SH:19][C:20]1[N:24]([CH3:25])[CH:23]=[N:22][N:21]=1>>[CH3:25][N:24]1[CH:23]=[N:22][N:21]=[C:20]1[S:19][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[N:5]=[CH:4][N:3]=[C:2]2[NH:13][C:14]1[S:15][CH:16]=[CH:17][N:18]=1

Participants

4

Reactant 3

HCID 21552-AminothiazoleHCID 111738094-Chloro-6-iodoquinazolineHCID 178481306HCID 178481306, compound

Product 1

HCID 11501028HCID 11501028, compound

Procedure

The compound of Example 2 was manufactured by the same method as in Example 1, by a similar method thereto or by a combination of such a method with a conventional method using 4-chloro-6-iodo-quinazoline, 2-amino-thiazole and 3-mercapto-4-methyl-1,2,4-triazole.

Sources & evidence

ORD record
ord-cdfbb082db944227a420e97aa78caeea
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

Loading…