Phenol → HCID 11508037, compound

HRID 2246274Notes

Reaction equation

HRID 2246274 reaction equation
Cl[C:2]1[C:3]2[N:11]=[C:10](Cl)[CH:9]=[CH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[NH2:13][C:14]1[S:15][CH:16]=[CH:17][N:18]=1.[C:19]1([OH:25])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[O:25]([C:10]1[CH:9]=[CH:8][C:4]2[N:5]=[CH:6][N:7]=[C:2]([NH:13][C:14]3[S:15][CH:16]=[CH:17][N:18]=3)[C:3]=2[N:11]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 3

HCID 996PhenolHCID 21552-AminothiazoleHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidine

Product 1

HCID 11508037HCID 11508037, compound

Procedure

The compound of Example 32 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 4,6-dichloro-pyrido[3,2-d]pyrimidine, 2-aminothiazole and phenol.

Sources & evidence

ORD record
ord-7f5b1a7afbac4ae181b76f4cbbed58fd
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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