2-Aminothiazole → HCID 11508403, compound

HRID 2246275Notes

Reaction equation

HRID 2246275 reaction equation
Cl[C:2]1[C:3]2[N:11]=[C:10](Cl)[CH:9]=[CH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[NH2:13][C:14]1[S:15][CH:16]=[CH:17][N:18]=1.[SH:19][C:20]1[N:24]([CH3:25])[CH:23]=[N:22][N:21]=1>>[CH3:25][N:24]1[CH:23]=[N:22][N:21]=[C:20]1[S:19][C:10]1[CH:9]=[CH:8][C:4]2[N:5]=[CH:6][N:7]=[C:2]([NH:13][C:14]3[S:15][CH:16]=[CH:17][N:18]=3)[C:3]=2[N:11]=1

Participants

4

Reactant 3

HCID 21552-AminothiazoleHCID 105841654,6-Dichloropyrido[3,2-d]pyrimidineHCID 178481306HCID 178481306, compound

Product 1

HCID 11508403HCID 11508403, compound

Procedure

The compound of Example 33 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 4,6-dichloro-pyrido[3,2-d]pyrimidine, 2-aminothiazole and 3-mercapto-4-methyl-1,2,4-triazole.

Sources & evidence

ORD record
ord-27102c456c6b4c818274f32c8f800655
Source dataset
uspto-grants-2010_03
Patent number
US07687502B2

Reaction notes

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