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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2246296Generated: October 31, 2026

1-Methyl-3-aminopyrazole → [6-(3-Cyano-pyridin-2-ylsulfanyl)-pyrido[3,2-d]-pyrimidin-4-yl]-(1-methyl-1H-pyrazol-3-yl)-amine

https://huagongshe.com/reaction/2246296

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-3-aminopyrazoleHCID 137254—
Reactant4,6-Dichloropyrido[3,2-d]pyrimidineHCID 10584165—
ReactantHCID 178510023HCID 178510023—
Product[6-(3-Cyano-pyridin-2-ylsulfanyl)-pyrido[3,2-d]-pyrimidin-4-yl]-(1-methyl-1H-pyrazol-3-yl)-amineHCID 23160270—

Reaction Steps

The compound of Example 60 was manufactured by the same method as in Example 31, by a similar method thereto or by a combination of such a method with a conventional method using 3-cyano-2-mercapto-pyridine, 3-amino-1-methyl-1H-pyrazole and 4,6-dichloro-pyrido[3,2-d]pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687502B2
Source datasetuspto-grants-2010_03
ORD IDord-c7c2a5113cfc41e2b230fd2470793b00
Source noteuspto-grants-2010_03