HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,4-Trifluorobenzene → 6-(2,4-difluorophenoxy)-N-(1-methyl-1H-pyrazol-3-yl)quinazolin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,4-Trifluorobenzene | HCID 67773 | — |
| Reactant | 1-Methyl-3-aminopyrazole | HCID 137254 | — |
| Reactant | 4-Chloroquinazolin-6-ol | HCID 23160273 | — |
| Product | 6-(2,4-difluorophenoxy)-N-(1-methyl-1H-pyrazol-3-yl)quinazolin-4-amine | HCID 11610032 | — |
Reaction Steps
The compound of Example 92 was manufactured by the same method as in Example 95, by a similar method thereto or by a combination of such a method with a conventional method using 1,2,4-trifluorobenzene, 3-amino-1-methyl-1H-pyrazole and 4-chloro-6-hydroxy-quinazoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687502B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-432ed69eeaf24c82a1f3aaefd243d76d |
| Source note | uspto-grants-2010_03 |