反应详情

To a solution of 0.11 g 1-chloro-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranos1-yl)-2-(4-methoxymethylethynyl-benzyl)-benzene in 2 mL methanol is added 0.85 mL of 1 M aqueous potassium hydroxide solution. The solution is stirred for 1 h at ambient temperature and then diluted with ethyl acetate. The resulting solution is washed with brine and dried over sodium sulfate. The solvent is evaporated and the residue is filtered through silica gel (dichloromethane/methanol 9:1->2:1).

1. washThe resulting solution is washed with brine
2. dry with materialdried over sodium sulfate
3. customThe solvent is evaporated
4. filtrationthe residue is filtered through silica gel (dichloromethane/methanol 9:1->2:1)