Imidazole → HCID 25260769, compound

Participants

Reaction Steps

A solution of Compound 11 (60 mg) and imidazole (37 mg) in dry N,N-dimethylformamide (1 mL) was heated at 70° C. for 16 hours under argon. The N,N-dimethylformamide was removed from the reaction mixture under vacuum and the residue was directly eluted on a silica gel column using 3% ethanol in dichloromethane to obtain the required product in 77% yield (45 mg).

Provenance & Evidence