4-Hexyl-2-methoxy-1-phenoxybenzene → 2-Methoxy-4-octyl-1-phenoxybenzene

HRID 2246760Notes

Reaction equation

HRID 2246760 reaction equation
[CH2:1]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:9]([O:20][CH3:21])[CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:22]([Mg]Cl)[CH2:23]CCCC.C([Mg]Cl)CCCCCCC>>[CH3:21][O:20][C:9]1[CH:8]=[C:7]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:22][CH3:23])[CH:12]=[CH:11][C:10]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 3

HCID 684255854-Hexyl-2-methoxy-1-phenoxybenzeneHCID 178443579HCID 178443579, compoundHCID 178444611HCID 178444611, compound

Product 1

HCID 684236592-Methoxy-4-octyl-1-phenoxybenzene

Procedure

The procedure as described above for synthesis of (4a) was used, except that hexyl magnesium chloride was replaced with octyl magnesium chloride. 1H NMR (300 MHz) (CDCl3): δ 7.36-6.90 (m, 8H), 3.90 (s, 3H), 2.69-2.65 (t, 2H), 1.72-1.68 (m, 2H), 1.42-1.36 (m, 10H), 1.00-0.94 (t, 3H).

Sources & evidence

ORD record
ord-e94fd878183243a2b79542fa9f100779
Source dataset
uspto-grants-2010_03
Patent number
US07687547B2

Reaction notes

Loading…