HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-(4-Nitrophenyl)-morpholin-3-ON
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(2-chloroethoxy)-N-(4-nitrophenyl)acetamide | HCID 11615857 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-(4-Nitrophenyl)-morpholin-3-ON | HCID 11447375 | — |
Reaction Steps
1.3 1 kg of “A1” is dissolved in 5 liters of acetonitrile at room temperature, 835 g of potassium carbonate are added, and the mixture is stirred at this temperature for 18 hours. The mixture is warmed to 50° and worked up analogously to Example 6, giving 4-(4-nitrophenyl)-3-oxomorpholine (“A2”), m.p. 150-152°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687624B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-b7623c50dd47441493dfdfc3dc886d17 |
| Source note | uspto-grants-2010_03 |