Ammonia → HCID 178516128, compound

Participants

Reaction Steps

5 g (0.036 mol) trifluoromethyldiethoxypentene acid ethyl ester (mixture of isomers) were dissolved in 40 g THF. The solution was metered during 150 minutes into a 250° C. hot tube reactor, which was filled with a boron doped zeolite catalyst. As carrier gas a mixture of 100 l N2/h and as reactant 50 l NH3/h were pumped through the reactor. The outcoming gas was cooled and quenched into THF yielding to a mixture auf 90% of the desired product as well as 5% 2-ethoxy-4-(trifluoromethyl)pyridine.

Provenance & Evidence