HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → HCID 60133537, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 53773721 | HCID 53773721 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 60133537 | HCID 60133537 | 77% |
Reaction Steps
The compound was prepared by reacting (S)-N-{3-[4-(4-oxo-piperidin-1-yl)-3,5-difluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide (0.5 mmol), ethylene glycol (0.5 mmol), p-toluene sulfonic acid (0.3 mmol) in toluene and by purifying on silica gel column chromatography to provide title compound in 77% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687627B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-5cf551c26d7e427b9c04bc848cb1681f |
| Source note | uspto-grants-2010_03 |