HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → (3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | (3-Bromopropyl)triphenylphosphonium bromide | HCID 2723862 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide | HCID 23651404 | 59% |
Reaction Steps
According to the teachings in EP 0235795, a suspension of 3-bromopropyltriphenylphosphonium bromide (Olo-IM4) in ethanol was reacted with 13.5 equivalents of an aqueous dimethylamine solution (50%) to provide dimethylaminopropyltriphenylphosphonium bromide HBr. After this reaction, the solvent was distilled off and the residue was recrystallized (yield: 59%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687646B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-9fba7a1b23e84769b52eb4af9364dcfe |
| Source note | uspto-grants-2010_03 |