Ethyl isocyanate → HCID 85861689, compound

Participants

Reaction Conditions

Reaction Steps

Ethyl isocyanate (0.09 ml, 1.1 mmol) is added to a stirred solution of 5-(4-methanesulfonyl-phenyl)-4-methyl-thiazol-2-ylamine (Example 58) (0.10 g, 0.37 mmol) in dimethylformamide (1.0 ml). The mixture is heated at 85° C. for 90 minutes followed by removal of the solvent. The residue is crystallised from ethyl acetate—methanol to afford the title compound. MH+ 340.0.

Provenance & Evidence