HCID 85861649, compound → HCID 85861650, compound

Participants

Reaction Steps

A stirred solution of 1-Ethyl-3-[4-methyl-5-(3-nitro-phenyl)-thiazol-2-yl]-urea (98c) (0.55 g, 1.8 mmol) in THF (25 ml) and EtOAc (50 ml) under Argon is treated with 10% palladium on carbon (1.0 g). The reaction mixture was placed under an atmosphere of hydrogen for 2 hours. The mixture was then filtered through Celite™ filter material and the solvent removed in vacuo to yield the titled compound.

Provenance & Evidence