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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2247393Generated: October 30, 2026

Hydrogen Bromide → HCID 86598444, compound

https://huagongshe.com/reaction/2247393

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantAcetylthioureaHCID 2723593—
ReactantThioureaHCID 2723790—
ReactantHCID 85861692HCID 85861692—
ReactantHCID 86761072HCID 86761072—
ProductHCID 86598444HCID 86598444—

Reaction Steps

The title compound is prepared as an HBr salt by the same procedure as N-[5-(4-fluoro-3-methoxy-phenyl)-4-methyl-thiazol-2-yl]-acetamide (161c) by replacing 1-bromo-1-(4-fluoro-3-methoxy-phenyl)-propan-2-one (161b) with 1-bromo-1-[4-chloro-3-(4-methyl-piperazine-1-sulfonyl)-phenyl]-propan-2-one (171c) and N-acetylthiourea with thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687637B2
Source datasetuspto-grants-2010_03
ORD IDord-3bc463143aae4c83adc19ad50cd78f9f
Source noteuspto-grants-2010_03