HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Chloro-3-(methylsulfonyl)phenyl)propan-2-one → 1-(3-(Methylsulfonyl)phenyl)propan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Chloro-3-(methylsulfonyl)phenyl)propan-2-one | HCID 57831108 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(3-(Methylsulfonyl)phenyl)propan-2-one | HCID 66588481 | — |
Reaction Steps
A solution of 1-(4-chloro-3-methanesulphonyl-phenyl)-propan-2-one (5.49 g, 22.28 mmol) in methanol (250 ml) is stirred under hydrogen in the presence of 10% Pd on carbon (3 g) for 2 hours. The reaction mixture is filtered and concentrated in vacuo to yield a yellow oil of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687637B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-20fabcc93d3a40bab64f586027cb1dbf |
| Source note | uspto-grants-2010_03 |