HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(3-(Methylsulfonyl)phenyl)propan-2-one | HCID 66588481 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-Bromo-1-(3-methanesulphonyl-phenyl)-propanone | HCID 85861653 | — |
Reaction Steps
A stirred solution of 1-(3-methanesulphonyl-phenyl)-propan-2-one (176b) (0.25 g, 1.18 mmol) in dioxane (10 ml) at 5° C. is treated with bromine (0.131 g, 0.82 mmol) added in two portions. The reaction is stirred and allowed to warm up to room temperature. The solvent is removed in vacuo to yield an orange oil of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687637B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-0a5f01175050466a8c1e5d5efcf254ae |
| Source note | uspto-grants-2010_03 |