反应详情

The title compound (26 mg) was synthesized in a yield of 64% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 2 (2e) using ethyl 1-{2-[5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]-4,5,6,7-tetrahydro-1-benzothien-4-yl}-azetidine-3-carboxylate (44 mg, 0.094 mmol) that was obtained in Example 8 (8g), lithium hydroxide monohydrate (8.7 mg, 0.20 mmol), and acetic acid (11 μl, 0.20 mmol).

1. customthe reaction similar to