反应详情

The title compound (77 mg) was synthesized in a yield of 39% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 1 (1g) using methyl 1-[(4-ethyl-5-{5-[4-(2-fluorophenoxy)phenyl]-1,2,4-oxadiazol-3-yl}-2-thienyl)methyl]azetidine-3-carboxylate (0.19 g, 0.38 mmol) that was obtained in Example 10 (10g), lithium hydroxide monohydrate (36 mg, 0.85 mmol), acetic acid (46 μL, 0.85 mmol), and oxalic acid (17 mg, 0.19 mmol).

1. customthe reaction similar to