HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 11978157, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 68523365 | HCID 68523365 | — |
| Product | HCID 11978157 | HCID 11978157 | 39.7% |
Reaction Steps
The title compound (77 mg) was synthesized in a yield of 38% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 2 (2e) using methyl 1-[(5-{5-[4-(2,3-difluorophenoxy)phenyl]-1,2,4-oxadiazol-3-yl}-4 ethyl-2-thienyl)methyl]azetidine-3-carboxylate (0.20 g, 0.39 mmol) that was obtained in Example 18 (18c), lithium hydroxide monohydrate (36 mg, 0.86 mmol), and acetic acid (47 μL, 0.86 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687491B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-5aa1f74ac40a4baf899ef36e88d85753 |
| Source note | uspto-grants-2010_03 |