1-[(4-Chlorophenyl)methyl]-4-(3-chloropropyl)piperazine → Hydrochloric Acid

Participants

Reaction Steps

1,4-Dimethyl-6-hydroxy-2-oxo-1,2-dihydroquinoline is reacted with 3-[4-(4-chlorobenzyl)-piperazin-1-yl]-propyl chloride in a manner analogous to that described in Example 3. There is obtained 1,4-dimethyl-6-{3-[4-(4-chlorobenzyl)-piperazin-1-yl]-propoxy}-2-oxo-1,2-dihydroquinoline in the form of a hydrochloride which melts, with decomposition, at 215°-220° C.

Provenance & Evidence