HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 24986921, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 68526846 | HCID 68526846 | — |
| Product | HCID 24986921 | HCID 24986921 | 96.3% |
Reaction Steps
The title compound (0.16 g) was synthesized in a yield of 95% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 3 (3e) using methyl 1-({3-ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl}methyl)azetidine-3-carboxylate (0.17 g, 0.36 mmol) that was obtained in Example 22 (22g), a 1 N aqueous solution of sodium hydroxide (1.1 mL, 1.1 mmol), and acetic acid (62 μL, 1.1 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07687491B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-172e864643164e6bb9e3acbf059f1832 |
| Source note | uspto-grants-2010_03 |