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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2247741Generated: November 1, 2026

Acetic Acid → HCID 24986921, compound

https://huagongshe.com/reaction/2247741

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 68526846HCID 68526846—
ProductHCID 24986921HCID 2498692196.3%

Reaction Steps

The title compound (0.16 g) was synthesized in a yield of 95% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 3 (3e) using methyl 1-({3-ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl}methyl)azetidine-3-carboxylate (0.17 g, 0.36 mmol) that was obtained in Example 22 (22g), a 1 N aqueous solution of sodium hydroxide (1.1 mL, 1.1 mmol), and acetic acid (62 μL, 1.1 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07687491B2
Source datasetuspto-grants-2010_03
ORD IDord-172e864643164e6bb9e3acbf059f1832
Source noteuspto-grants-2010_03