Sodium Hydroxide → 1-({6-Ethyl-5-[5-(4-isobutyl-3-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl}methyl)azetidine-3-carboxylic acid

Participants

Reaction Steps

The title compound (0.10 g) was synthesized in a yield of 82% as a white crystalline solid by conducting the reaction similar to that mentioned in Example 3 (3e) using methyl 1-({6-ethyl-5-[5-(4-isobutyl-3-methylphenyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl}methyl)azetidine-3-carboxylate (0.13 g, 0.29 mmol) that was obtained in Example 29 (29b) and a 1 N aqueous solution of sodium hydroxide (0.87 mL, 0.87 mmol).

Provenance & Evidence